Volume : V, Issue : V, September - 2021
Background: The aim of good postoperative analgesia is to produce a long lasting, continuous effective analgesia with minimum side effects. Adding, an intrathecal adjuvant to local anaesthetics forms a reliable method to prolong the duration of anaesthesia. The present study was undertaken to compare the effects of Nalbuphine with Dexmedetomidine when used intrathecally as an adjuvant to 0.5% Bupivacaine in spinal anaesthesia and its postoperative analgesic characteristics. Method: Total 60 patients of either sex, age between 18-60 years, ASA class I and II undergoing elective lower abdominal surgeries under subarachnoid block were enrolled and divided into two groups of 30 each. Group A received Inj. dexmedetomidine 10g with bupivacaine 15mg and group B received Inj. nalbuphine 0.5 mg with Inj. bupivacaine 15 mg intrathecally. Patients were assessed for sensory and motor characteristics, quality and duration of effective analgesia, hemodynamic changes and side effects. Results: Dexmedetomidine as adjuvant with bupivacaine fasten the onset and prolong the duration of sensory and motor block as well as prolonged the duration of analgesia as compared to Nalbuphine. Dexmedetomidine has delayed two segment regression times (154.197.86 minutes) than Nalbuphine (126.61 5.68 minutes). Both the drugs provide stable hemodynamic and respiratory profile and have no significant adverse effects in intra and post-operative period. Conclusion: Dexmedetomidine is a useful adjuvant in subarachnoid block and, prolongs postoperative analgesia as compared to Nalbuphinewhen used intrathecallyin spinal anaesthesia.
COMPARISON OF NALBUPHINE AND DEXMEDETOMIDINE AS ADJUVANT WITH INTRA-THECALHYPERBARIC 0.5% BUPIVACAINE ON SPINAL ANAESTHESIA AND ITS POSTOPERATIVE ANALGESIC CHARACTERISTICS, Dr. Santosh Gitte, Dr Gajanand Karshayal, INTERNATIONAL JOURNAL OF ADVANCED MEDICINE : Volume-5 | Issue-5 | September-2021